Converging on a mechanism for choline degradation
نویسندگان
چکیده
منابع مشابه
Converging on a mechanism for choline degradation.
I n PNAS, Craciun and Balskus (1) combine biochemical intuition with modern genome mining techniques to discover the elusive enzyme responsible for catalyzing the degradation of choline (1, Scheme 1). Choline is an essential nutrient in higher organisms that is required for the biosynthesis of the neurotransmitter acetylcholine and the head group of several phospholipids, and that serves as a s...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2012
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1219534110